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After completing the first set of experiments, results showed the compound Delta-tetrahydrocannabinol [THC] inhibited EGF-induced growth and migration in epidermal growth factor receptor (EGFR) expressing non-small cell lung cancer cell lines. Lung cancers that over-express EGFR are usually are found highly aggressive and resistant to chemotherapy. The introduction of CB1 and CB2 is similar to endocannabinoids [naturally produced in the brain by everyone] activates these receptors. Researchers suggest that the THC activating these receptors may be used in a targeted fashion to treat lung cancer. Whereas the current leading treatment (chemotherapy) attacks every part of the body. Anju Preet, Ph.D., a researcher in the Division of Experimental Medicine, stated, “if used prudently, [THC] may offer a new road to therapy against lung cancer.” Can someone say prevention as well?
The above writing is summarized from materials provided by American Association for Cancer Research, http://www.aacr.org/
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